Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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1,066
Tocris Bioscience™ BRD 73954
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Dual histone deacetylase (HDAC) 6/8 inhibitor
| CAS | 1440209-96-0 |
|---|---|
| Chemical Name or Material | N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C16H16N2O3 |
| Formula Weight | Observed MW: 284.31 |
| Assay Percent Range | >98% |
1,067
Tocris Bioscience™ Clozapine N-oxide dihydrochloride
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Activator of muscarinic DREADDs; water soluble version of Clozapine N-oxide (Cat. No. 4936)
| Target | DREADD Activators |
|---|---|
| CAS | 2250025-93-3 |
| Purity | 99% |
| Chemical Name or Material | 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C18H19ClN4O0.2 HCl |
| Formula Weight | Observed MW: 415.74 |
| Assay Percent Range | >99% |
1,068
Tocris Bioscience™ DIM-C-pPhOH
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Nur77 antagonist
| CAS | 151358-47-3 |
|---|---|
| Chemical Name or Material | 1,1-Bis(3'-indolyl)-1-(p-hydroxyphenyl)methane |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H18N2O |
| Formula Weight | Observed MW: 338.408 |
| Assay Percent Range | >98% |
1,069
Tocris Bioscience™ DL-AP4
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CAS: 20263-07-4 Molecular Formula: C4H10NO5P
| CAS | 20263-07-4 |
|---|---|
| Molecular Formula | C4H10NO5P |
1,070
Tocris Bioscience™ Imatinib mesylate
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Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
1,071
Tocris Bioscience™ Adaptaquin
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HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
| Target | Hydrolase Inhibitors |
|---|---|
| CAS | 385786-48-1 |
| Purity | >97% |
| Chemical Name or Material | 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H16ClN3O2 |
| Formula Weight | 377.82 |
1,072
Tocris Bioscience™ SR 16584
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CAS: 1150153-86-8 Molecular Formula: C17H22N2O
| CAS | 1150153-86-8 |
|---|---|
| Molecular Formula | C17H22N2O |
1,073
Tocris Bioscience™ TTNPB
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CAS: 71441-28-6 Molecular Formula: C24H28O2
| CAS | 71441-28-6 |
|---|---|
| Molecular Formula | C24H28O2 |
1,074
Tocris Bioscience™ Dipyridamole
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CAS: 58-32-2 Molecular Formula: C24H40N8O4
| CAS | 58-32-2 |
|---|---|
| Molecular Formula | C24H40N8O4 |
1,075
Tocris Bioscience™ Anpirtoline hydrochloride
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CAS: 99201-87-3 Molecular Formula: C10H14Cl2N2S
| CAS | 99201-87-3 |
|---|---|
| Molecular Formula | C10H14Cl2N2S |
1,076
Tocris Bioscience™ DIPPA hydrochloride
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CAS: 155512-52-0 Molecular Formula: C22H24Cl3N3OS
| CAS | 155512-52-0 |
|---|---|
| Molecular Formula | C22H24Cl3N3OS |
1,077
Tocris Bioscience™ SM-21 maleate
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CAS: 155059-42-0 Molecular Formula: C22H28ClNO7
| CAS | 155059-42-0 |
|---|---|
| Molecular Formula | C22H28ClNO7 |
1,078
Tocris Bioscience™ (R)-Baclofen
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CAS: 69308-37-8 Molecular Formula: C10H12ClNO2
| CAS | 69308-37-8 |
|---|---|
| Molecular Formula | C10H12ClNO2 |
1,079
Tocris Bioscience™ Pomalidomide 4'-alkylC7-amine
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry
1,080
Tocris Bioscience™ CRT 0066101
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Potent protein kinase D (PKD) inhibitor